Description

GHRP-2 is a synthetic growth hormone secretagogue (GHS) and ghrelin receptor (GHSR-1a) agonist that triggers the pulsatile release of endogenous growth hormone from the anterior pituitary. As a second-generation GHRP, it is considered more potent than GHRP-6 in stimulating GH secretion, while producing a comparatively milder effect on hunger.

Research has focused on GHRP-2’s capacity to enhance protein synthesis, support muscle growth, and aid in tissue repair, making it relevant in studies on physical recovery, sarcopenia, and age-related hormonal decline. It also affects IGF-1 levels, contributing to improved regenerative processes and metabolic efficiency.

GHRP-2 has been studied for its potential influence on bone density, immune modulation, and cardiovascular health, as well as its interaction with cortisol and prolactin secretion—an important consideration in endocrine studies. Its strong GH-releasing properties and diverse physiological effects make it a widely used peptide in both clinical and preclinical hormonal research.